The epigenetic underpinnings of memory are still poorly understood. A study provides a causal link between the epigenetic dynamics of a single genomic locus in engram cells and memory formation, achieved by the development of a reversible epigenetic editing tool.
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Mauger, O., Binder, E.B. Unlocking the epigenetic secrets of memory. Nat Genet 57, 2621–2622 (2025). https://doi.org/10.1038/s41588-025-02369-x
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DOI: https://doi.org/10.1038/s41588-025-02369-x