Extended Data Fig. 7: Gene set enrichment results for top 10 GenePrio genes and GO:BP. | Nature Genetics

Extended Data Fig. 7: Gene set enrichment results for top 10 GenePrio genes and GO:BP.

From: Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases

Extended Data Fig. 7

Heatmap of significant (adjusted P < 5 × 10−6) gene sets for GO:BP, showing top 10 GenePrio genes (GenePrio sum = 4) and their affiliation to each set. The enrichment testing is done using a Fisher’s one-sided test (cumulative hypergeometric probability). P-values were adjusted for multiple testing using the g:SCS algorithm from the g:Profiler tool. BP, biological process; GO, gene ontology.

Back to article page