Fig. 3: Joint multiancestry meta-analysis of the discovery and replication cohorts. | Nature Genetics

Fig. 3: Joint multiancestry meta-analysis of the discovery and replication cohorts.

From: Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves prediction across ancestry groups

Fig. 3

Only genome-wide significant associations (P < 5 × 10−8) are plotted. The joint analysis (n = 296,754 discovery, plus n = 95,768 replication) detected 447 independent genome-wide significant PSA-associated variants. These included 111 novel variants that were conditionally independent from previous findings and the discovery-only analyses (indicated by the circles). Gene labels are given for variants with CADD > 15 and/or variants that are prostate tissue eQTLs. Results are from a fixed effects meta-analysis of GWAS performed using linear regression. All P values are two-sided.

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