Extended Data Fig. 2: Projection of contributing studies samples into the same PC space. | Nature

Extended Data Fig. 2: Projection of contributing studies samples into the same PC space.

From: Mapping the human genetic architecture of COVID-19

Extended Data Fig. 2

We asked participating studies to perform a PC projection using the 1000 Genomes Project and Human Genome Diversity Project as a reference, with a common set of variants. For each panel (except for the reference), coloured points correspond to contributed samples from each cohort, whereas grey points correspond to the reference samples from the 1000 Genomes Project. Colour represents a genetic population that each cohort specified. As 23andMe, Genomics England 100,000 Genomes Project (GenomicsEngland100kgp), and Million Veterans Program (MVP) only submitted PCA images, we overlaid their submitted transparent images using the same coordinates, instead of directly plotting them. Populations are defined as African (AFR), admixed American (AMR), East Asian (EAS), European (EUR), Middle Eastern (MID) and South Asian (SAS), Oceanian (OCE).

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