Extended Data Fig. 7: Cluster-specific associations of index SNVs with the first two axes of genetic variation in T2D cases and controls. | Nature

Extended Data Fig. 7: Cluster-specific associations of index SNVs with the first two axes of genetic variation in T2D cases and controls.

From: Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

Extended Data Fig. 7

a, Unadjusted for BMI. b, Adjusted for study-level mean BMI. Each point corresponds to a cluster, plotted according to the mean z-score for association with the first two axes of genetic variation (PC1 and PC2) on the x axis and y axis, respectively. Grey bars correspond to 95% confidence intervals. The liver and lipid metabolism cluster has been removed for ease of presentation.

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