Extended Data Fig. 1: Detection of influenza A/H1pdm and A/H3 virus variants carrying a mutation at amino acid position 38 of PA in patients. | Nature Microbiology

Extended Data Fig. 1: Detection of influenza A/H1pdm and A/H3 virus variants carrying a mutation at amino acid position 38 of PA in patients.

From: Influenza A variants with reduced susceptibility to baloxavir isolated from Japanese patients are fit and transmit through respiratory droplets

Extended Data Fig. 1

a, b, Respiratory tract specimens were obtained from pediatric (aged 0 to 15 years) and adult (16 years or older) patients before and after baloxavir marboxil therapy and from untreated patients with influenza A/H1pdm (a) and A/H3 (b) virus infections in Japan during the 2018–2019 influenza season. The nucleotide sequences of the PA genes of the viruses in the specimens were determined by means of Sanger sequencing. c, Timeline of the clinical course of the two patients (GR125 and GR142) with influenza A/H3N2 virus infection.

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