Fig. 6: Limited overlap between DV genes and DE genes across three case studies. | npj Systems Biology and Applications

Fig. 6: Limited overlap between DV genes and DE genes across three case studies.

From: Exploring cell-to-cell variability and functional insights through differentially variable gene analysis

Fig. 6

Venn diagrams showing the overlap between DV genes identified by spline-DV and DE genes identified by three statistical approaches: Wilcoxon Rank-Sum Test, DESeq2, and MAST. In each panel, DE genes are split into down-regulated (DE Down) and up-regulated (DE Up) groups and overlap with DV genes is depicted separately. The numbers represent the counts of genes unique to each category and those shared across categories. Panels A–C represent results from three different data sets of case studies: A diet-induced obesity, B liver fibrosis, and C colorectal cancer.

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