Abstract
The study of respiratory mechanics in infants requires a noninvasive accurate measurement of the lung volume changes (ΔVL). Optoelectronic plethysmography (OEP) allows the assessment of ΔVL through the measurement of the chest wall surface motion and it has been proved to be accurate in adults. The aim of this study was to apply OEP to newborns and to validate it by comparison to pneumotachography. Twenty term and preterm newborns (GA = 34 ± 5 wk) in stable condition were studied during 1 to 2 min periods of quiet breathing in supine position. Airway opening flow was measured by applying a facemask connected to a pneumotachograph (PNT) and integrated to provide the ΔVL. Chest wall volume changes were simultaneously measured by OEP. The tidal volume values measured by pneumotachography and by OEP were compared for each breath. A total of 771 breaths from all patients were considered. Bland-Altmann analysis showed a mean difference of −0.08 mL and a limit of agreement ranging from −2.98 to 2.83 mL. Linear regression analysis demonstrated good correlation between the two techniques (r2 = 0.95, q = 1.00 mL, m = 0.96). OEP provides accurate measurements of ΔVL in newborns and may be useful to study respiratory mechanics and breathing patterns during spontaneous breathing and mechanical ventilation.
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Abbreviations
- AB%:
-
percentage contribution of the abdomen to VT,CW
- %diff:
-
percentage difference between VT,L and VT,CW
- ΔVL:
-
lung volume changes
- EELV:
-
end-expiratory lung volume
- θ:
-
phase angle
- PNT:
-
pneumotachograph
- OEP:
-
optoelectronic plethysmography
- RIP:
-
respiratory inductive plethysmography
- V CW :
-
chest wall volume
- V T,L :
-
tidal volume computed from ΔVL
- V T,CW :
-
chest wall tidal volume
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Acknowledgements
We thank Daniela Biolo, Alberto Chemotti, Chiara Veneroni, and Francesca Pennati from Politecnico di Milano and Valeria Zimbaldi, Roberta Corbetta, and Francesca Furlan from Ospedale S. Gerardo for their technical support and assistance during the experimental activity.
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Supported, in part, by the Istituto Italiano Tecnologico (IIT), Politecnico di Milano Unit.
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Dellaca', R., Ventura, M., Zannin, E. et al. Measurement of Total and Compartmental Lung Volume Changes in Newborns by Optoelectronic Plethysmography. Pediatr Res 67, 11–16 (2010). https://doi.org/10.1203/PDR.0b013e3181c0b184
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DOI: https://doi.org/10.1203/PDR.0b013e3181c0b184
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