Coloured scanning electron micrograph of human cells infected with bird flu virus. The virus shown here in green is budding from viral filaments

Antibody drugs show promise for treating bird flu and HIV

Scientists are developing antibodies to track the evolution of these viruses and better treat infections.

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  • A multipass optical parametric amplifier leverages dispersion-engineered dielectric mirrors to overcome the gain versus bandwidth trade-off and achieve broadband amplification with high gain within a compact device.

    • Jan H. Nägele
    • Tobias Steinle
    • Harald Giessen
    Article
  • The ferroptosis suppressor protein FSP1 has a critical role in ferroptosis protection of tumours across multiple in vivo models and is linked to worse prognosis in human lung adenocarcinoma, suggesting its potential as a therapeutic target in lung cancer.

    • Katherine Wu
    • Alec J. Vaughan
    • Thales Papagiannakopoulos
    ArticleOpen Access
  • Live-cell imaging of mRNA encoding secretome proteins and translated nascent peptide markers show that secretome translation occurs at endoplasmic reticulum junctions near lysosomes, requires lunapark protein and is modulated by nutrient status.

    • Heejun Choi
    • Ya-Cheng Liao
    • Jennifer Lippincott-Schwartz
    ArticleOpen Access
  • A method using subtree pruning and regrafting-based tree assessment (SPRTA), which considers evolutionary relationships between lineages, enhances interpretability of phylogenetic analyses such as those of SARS-CoV-2 variants.

    • Nicola De Maio
    • Nhan Ly-Trong
    • Nick Goldman
    ArticleOpen Access
Donald Trump stands at a podium speaking into a microphone, holding up some paperwork.

How Trump 2.0 is reshaping science

Since US President Donald Trump took office in January 2025, his team has made major changes to the federal government that have disrupted research and research institutions in the United States and beyond.
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