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10 result(s) for 'author#Brian W. Kunkle' within BMC

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  1. Both Alzheimer’s disease (AD) genetic risk factors and indices of cognitive reserve (CR) influence risk of cognitive decline, but it remains unclear whether they interact. This study examined whether a CR inde...

    Authors: Corinne Pettigrew, Jurijs Nazarovs, Anja Soldan, Vikas Singh, Jiangxia Wang, Timothy Hohman, Logan Dumitrescu, Julia Libby, Brian Kunkle, Alden L. Gross, Sterling Johnson, Qiongshi Lu, Corinne Engelman, Colin L. Masters, Paul Maruff, Simon M. Laws…
    Citation: Alzheimer's Research & Therapy 2023 15:66
  2. MAPT encodes for tau, the predominant component of neurofibrillary tangles that are neuropathological hallmarks of Alzheimer’s disease (AD). Genetic association of MAPT variants with l...

    Authors: Mariet Allen, Michaela Kachadoorian, Zachary Quicksall, Fanggeng Zou, High Seng Chai, Curtis Younkin, Julia E Crook, V Shane Pankratz, Minerva M Carrasquillo, Siddharth Krishnan, Thuy Nguyen, Li Ma, Kimberly Malphrus, Sarah Lincoln, Gina Bisceglio, Christopher P Kolbert…
    Citation: Alzheimer's Research & Therapy 2014 6:39
  3. Limited ancestral diversity has impaired our ability to detect risk variants more prevalent in ancestry groups of predominantly non-European ancestral background in genome-wide association studies (GWAS). We c...

    Authors: Farid Rajabli, Penelope Benchek, Giuseppe Tosto, Nicholas Kushch, Jin Sha, Katrina Bazemore, Congcong Zhu, Wan-Ping Lee, Jacob Haut, Kara L. Hamilton-Nelson, Nicholas R. Wheeler, Yi Zhao, John J. Farrell, Michelle A. Grunin, Yuk Yee Leung, Pavel P. Kuksa…
    Citation: Genome Biology 2025 26:210
  4. Although genome-wide association studies (GWAS) have successfully located various genetic variants susceptible to Alzheimer’s Disease (AD), it is still unclear how specific variants interact with genes and tis...

    Authors: Brian Lee, Xiaohui Yao and Li Shen
    Citation: BMC Genomics 2022 23(Suppl 4):414

    This article is part of a Supplement: Volume 23 Supplement 4

  5. Cognitive resilience (CR) contributes to the variability in risk for developing and progressing in Alzheimer’s disease (AD) among individuals. Beyond genetics, recent studies highlight the critical role of lif...

    Authors: Wei Zhang, David Lukacsovich, Juan I. Young, Lissette Gomez, Michael A. Schmidt, Eden R. Martin, Brian W. Kunkle, X. Steven Chen, Deirdre M. O’Shea, James E. Galvin and Lily Wang
    Citation: Alzheimer's Research & Therapy 2025 17:88
  6. More than 75 common variant loci account for only a portion of the heritability for Alzheimer’s disease (AD). A more complete understanding of the genetic basis of AD can be deduced by exploring associations w...

    Authors: Moonil Kang, Ting Fang Alvin Ang, Sherral A. Devine, Richard Sherva, Shubhabrata Mukherjee, Emily H. Trittschuh, Laura E. Gibbons, Phoebe Scollard, Michael Lee, Seo-Eun Choi, Brandon Klinedinst, Connie Nakano, Logan C. Dumitrescu, Alaina Durant, Timothy J. Hohman, Michael L. Cuccaro…
    Citation: Molecular Neurodegeneration 2023 18:40
  7. Simultaneous consideration of two neuropathological traits related to Alzheimer’s disease (AD) has not been attempted in a genome-wide association study.

    Authors: Jaeyoon Chung, Xiaoling Zhang, Mariet Allen, Xue Wang, Yiyi Ma, Gary Beecham, Thomas J. Montine, Steven G. Younkin, Dennis W. Dickson, Todd E. Golde, Nathan D. Price, Nilüfer Ertekin-Taner, Kathryn L. Lunetta, Jesse Mez, Richard Mayeux, Jonathan L. Haines…
    Citation: Alzheimer's Research & Therapy 2018 10:22
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