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Table 2 Diagnostic outcomes of included screening examinations

From: Triaging mammography with artificial intelligence: an implementation study

 

AI result

Radiologist recommendation after screening

Radiologist recommendation after diagnostic workup

Final pathology

463

Experimental Group

AI-modified workflow (Fig. 2)

131

Prioritized by AI

28% (131/463)

33

Additional imaging needed (BIRADS 0)

25% (33/131)

12 Tissue diagnosis (BIRADS 4 or 5)

3 Cancer

9 Benign

19 Annual Screening (BIRADS 1 or 2)

N/A

2 Short term follow-up (BIRADS 3)

0 No diagnostic workup

98

Annual Screening (BIRADS 1 or 2)

75% (98/131)

N/A

1 Benign (detected on screening MRI)

332

Not Prioritized by AI

72% (332/463)

46

Additional imaging needed (BIRADS 0)

14% (46/332)

6 Tissue diagnosis needed (BIRADS 4 or 5)

0 Cancer

6 Benign

25 Annual Screening (BIRADS 1 or 2)

N/A

9 Short term follow-up

(BIRADS 3)

6 No diagnostic workup

286

Annual Screening (BIRADS 1 or 2)

86% (286/332)

N/A

 

392 Control Group

Standard workflow (Fig. 2)

AI results do not impact participant or radiologist workflow

AI not used to prioritize

56

Additional imaging needed (BIRADS 0)

14% (56/392)

15 Tissue diagnosis needed (BIRADS 4 or 5)

3 Cancer

12 Benign

29 Annual Screening (BIRADS 1 or 2)

N/A

9 Short term follow-up (BIRADS 3)

3 No diagnostic workup

336

Annual Screening (BIRADS 1 or 2)

86% (336/392)

N/A

1 Cancer (detected on screening MRI)

1 Benign (detected on screening MRI)

  1. Diagnostic outcomes after screening, additional imaging and tissue biopsy based on AI prioritization categorization. Screening mammograms were assigned BIRADS category 1 (negative), 2 (benign) or 0 (incomplete—additional imaging needed) after radiologist review. After additional diagnostic imaging, a BIRADS category was assigned as 1 (negative), 2 (benign), 3 (probably benign), 4 (suspicious), 5 (highly suggestive of malignancy). In 3 cases AI integration with site software failed due to a software error. BIRADS Breast Imaging Reporting & Data System