diff --git a/scripts/build/setup/termux_setup_python_pip.sh b/scripts/build/setup/termux_setup_python_pip.sh
index 90ea99897bd2a2..cecb3ee2e08e07 100644
--- a/scripts/build/setup/termux_setup_python_pip.sh
+++ b/scripts/build/setup/termux_setup_python_pip.sh
@@ -1,4 +1,5 @@
 termux_setup_python_pip() {
+	unset PYTHONPYCACHEPREFIX
 	if [ "$TERMUX_ON_DEVICE_BUILD" = "true" ]; then
 		if [[ "$TERMUX_APP_PACKAGE_MANAGER" = "apt" && "$(dpkg-query -W -f '${db:Status-Status}\n' python-pip 2>/dev/null)" != "installed" ]] ||
 		[[ "$TERMUX_APP_PACKAGE_MANAGER" = "pacman" && ! "$(pacman -Q python-pip 2>/dev/null)" ]]; then
diff --git a/scripts/build/termux_step_massage.sh b/scripts/build/termux_step_massage.sh
index 2a1bb1f5b8d0b4..227dc7996466c6 100644
--- a/scripts/build/termux_step_massage.sh
+++ b/scripts/build/termux_step_massage.sh
@@ -118,12 +118,6 @@ termux_step_massage() {
 		done < <(find ./${ADDING_PREFIX}share/man -type l ! -iname \*.gz -print0)
 	fi
 
-	# Remove python-glibc package files that are created
-	# due to its launch during package compilation.
-	if [ "$TERMUX_PACKAGE_LIBRARY" = "glibc" ] && [ "$TERMUX_PKG_NAME" != "python-glibc" ]; then
-		rm -f ./${ADDING_PREFIX}lib/python${TERMUX_PYTHON_VERSION}/__pycache__/{base64,platform,quopri}.cpython-${TERMUX_PYTHON_VERSION//./}.pyc
-	fi
-
 	# Check so files were actually installed. Exclude
 	# share/doc/$TERMUX_PKG_NAME/ as a license file is always
 	# installed there.
diff --git a/scripts/build/termux_step_setup_variables.sh b/scripts/build/termux_step_setup_variables.sh
index b63c908f3945a8..6ab62a71b45ce6 100644
--- a/scripts/build/termux_step_setup_variables.sh
+++ b/scripts/build/termux_step_setup_variables.sh
@@ -189,6 +189,8 @@ termux_step_setup_variables() {
 	TERMUX_PKG_MESON_NATIVE=false
 	TERMUX_PKG_CMAKE_CROSSCOMPILING=true
 
+	export PYTHONPYCACHEPREFIX=$TERMUX_COMMON_CACHEDIR-$TERMUX_ARCH
+
 	unset CFLAGS CPPFLAGS LDFLAGS CXXFLAGS
 	unset TERMUX_MESON_ENABLE_SOVERSION # setenv to enable SOVERSION suffix for shared libs built with Meson
 }